Unravelling the Enigma: A Study on Exploring the Idiopathic Surge in Serum Alkaline Phosphatase Level

  • Authors

    • Vishal KR Dr. Chandramma Dayananda Sagar Institute of Medical Education and Research
    2024-03-16
    https://doi.org/10.14419/3fvczb37
  • A 73 year old Indian female with type O blood group came for routine checkup when it was discovered she had elevated levels of serum alkaline phosphatase (600 mg/dL). Other liver function tests were within normal limits. Abdominal imaging revealed grade I fatty liver but an extensive serological search for significant hepatobiliary disease was negative. She is currently under medication for diabetes and hypertension, association with raised enzyme level couldn't be interpreted due to paucity of testing.

  • References

    1. Persistently elevated alkaline phosphatase - Jitin Verma and David A Gorard
    2. Ockner R. Alkaline phosphatase. In: Liver, gallbladder and biliary disease, Cecil textbook of medicine. 20th edn Philadelphia: W. B. Saunders, 1996.
    3. Kutoh E. Possible metformin-induced hepatotoxicity. Am J Geriatr Pharmacother. 2005;3:270–3. https://doi.org/10.1016/j.amjopharm.2005.12.002.
    4. An Update on Drug-induced Liver Injury, Harshad Devarbhavi.
    5. Vuppalanchi R., Liangpunsakul S., Chalasani N. Etiology of new-onset jaundice: how often is it caused by idiosyncratic drug-induced liver injury in the United States.
    6. Association of serum alkaline phosphatase and depression in US adults: a population-based cross-sectional study, by Yujiang Liang et al.
  • Downloads

  • How to Cite

    KR, V. (2024). Unravelling the Enigma: A Study on Exploring the Idiopathic Surge in Serum Alkaline Phosphatase Level. International Journal of Medicine, 12(1), 20-22. https://doi.org/10.14419/3fvczb37