Synthetic Biology for Drug Discovery: Unlocking New ‎Therapeutic Pathways

  • Authors

    • Dr. L. Kaviarasan Assistant Professor, Department of Pharmacy, Sathyabama Institute of Science and Technology, Chennai, Tamil Nadu, India
    • Vibhor Mahajan Center of Research Impact and Outcome, Chitkara University, Rajpura, Punjab, India
    • Sourav Rampal Chitkara Center for Research and Development, Chitkara University, Himachal Pradesh, India
    • H. D. Raghavendra Prasad Assistant Professor, Department of Civil Engineering, Faculty of Engineering and Technology, JAIN (Deemed-to-be University)، ‎Ramnagar District, Karnataka, India
    • Dr. Naresh Kaushik Assistant Professor, uGDX, ATLAS SkillTech University, Mumbai, India
    • Dr. Snigdha Pattnaik Professor, Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to be University)، ‎Bhubaneswar, Odisha, India
    • Shitij ‎ Goyal Quantum University Research Center, Quantum University, Roorkee, Uttarakhand, India
    https://doi.org/10.14419/cehxkd95

    Received date: May 2, 2025

    Accepted date: May 31, 2025

    Published date: October 31, 2025

  • Pharmaceutical; Mechanisms; Discovery; Communicate

  • Abstract

    The goal of this study, which employs a Data Mining Algorithm, is to pinpoint the functional groups and their connectivity chains in ‎phytochemicals that are used for diabetes treatment. We’ll also compare these with Acarbose, a synthetic drug currently prescribed for ‎diabetes management. Plants produce chemical substances to defend themselves against predators and parasites, and these protective ‎compounds are known as phytochemicals. They can be quite effective as drugs. However, figuring out the similarities between different ‎molecules poses a significant challenge in both drug discovery and molecular biology. This challenge is crucial because the biochemical ‎properties of a molecule are closely tied to its structure. The molecular structure of organic compounds primarily consists of carbon, ‎hydrogen, nitrogen, and oxygen atoms. Among these, carbon is particularly important as it forms the backbone of these compounds. The ‎arrangement of carbon atoms is key to naming the compound and influences its physical and chemical properties. Together with hydrogen ‎and oxygen, these atoms create normal functional groups that link together to form various functional group chains. Chains with the same ‎functional groups tend to undergo similar chemical reactions. Therefore, identifying these functional group chains in phytochemicals is quite ‎a complex task.

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  • How to Cite

    Kaviarasan , D. L. ., Mahajan , V. ., Rampal , S. ., Prasad , H. D. R. ., Kaushik , D. N. ., Pattnaik, D. S. ., & Goyal , S. ‎. (2025). Synthetic Biology for Drug Discovery: Unlocking New ‎Therapeutic Pathways. International Journal of Basic and Applied Sciences, 14(SI-1), 423-427. https://doi.org/10.14419/cehxkd95