Synthesis and Electrochemical Behavior of Some New Pyridazine Derivatives

  • Authors

    • Essam Abdelghani
    • Wesam saber Shehab lecture of Organic chemistry zagazig unversty faculty of science egypt
    • Medhat El-Mobayed
    • Atef M. Abdel Hamid
    2012-06-26
    https://doi.org/10.14419/ijbas.v1i3.87
  • One-pot reaction of 1 with ethyl cyanoacetate and/or benzylidenemalono- nitrile afforded pyridazine derivatives 2 and 3, respectively. Compound 2 was subjected to some reactions to produce other new pyridazine derivatives. Also, treatment of 2 with hydrazine hydrate in ethanol gave the carbohydrazide 7. Some derivatives of the latter compound have been synthesized. Cyclic voltammograms of compounds 2, 5b, 7 and 8b using an undivided cell at platinum electrodes are discussed. The antimicrobial activity of some synthesized derivatives has been investigated.

    Author Biography

    • Wesam saber Shehab, lecture of Organic chemistry zagazig unversty faculty of science egypt
      Department of Chemistry
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  • How to Cite

    Abdelghani, E., Shehab, W. saber, El-Mobayed, M., & Abdel Hamid, A. M. (2012). Synthesis and Electrochemical Behavior of Some New Pyridazine Derivatives. International Journal of Basic and Applied Sciences, 1(3), 220-236. https://doi.org/10.14419/ijbas.v1i3.87