Real-World Evaluation of Dual-Axis Barbed PDOKnotless Sutures in Elective Soft ‎Tissue Closure:A Multicenter Observational Study

  • Authors

    • Ankur K. Patel Dynamic Super Speciality Hospital, 401,402 Dynamic House, Opp Child Care ‎Hospital Station, Navrangpura, Ahmedabad, Gujarat, India- 380009
    • Jayant Trivedi Prajna Health Care Hospital, 205-208, Aagam Avenue, Acher, Near Adani CNG ‎Pump, Sabarmati, Ahmedabad, Gujarat, India -380005‎
    • Hamikchandra Patel Shaleen Multispecialty Hospital, Shaleen Plaza, Mangaldeep Party Plot, Nr. Sukan ‎Mall Cross Road, Science City Road - Sola, Ahmedabad, Gujarat, India - 380 060
    • Sheetal Nikunj Parmar Department of Product Performance Engineering & Post Market Clinical Follow Up, Meril Life Sciences, Vapi, ‎Gujarat, India -396191
    • Janvi ‎ Shah Department of Product Performance Engineering & Post Market Clinical Follow Up, Meril Life Sciences, Vapi, ‎Gujarat, India -396191
    • Kiran Kumar Shetty Department of Product Performance Engineering & Post Market Clinical Follow Up, Meril Life Sciences, Vapi, ‎Gujarat, India -396191
    https://doi.org/10.14419/dmr9kg13

    Received date: November 15, 2025

    Accepted date: December 11, 2025

    Published date: February 14, 2026

  • Barbed Sutures; Knotless Sutures; Polydioxanone; Surgical Wound Closure; Tissue ‎Approximation.

  • Abstract

    Background: The knotless barbed sutures are designed to overcome the problems of ‎traditional knotted sutures through their ability to prevent knot slippage and maintain uniform ‎tension. The absorbable polydioxanone knotless suture PINION™ PDO with dual-axis barbs ‎provides both secure and efficient wound closure.‎

    Aim: The study design aims to assess the clinical performance and safety aspects ‎of PINION™ PDO sutures during soft tissue approximation ‎

    Methodology: The retrospective, multicenter observational research included 114 patients ‎who maintained complete follow-up data throughout 12 months. The study documented ‎demographic details along with wound characteristics, suture usage, closure time, and ‎complications at three different time points: discharge, 2 months, and 12 months.‎

    Results: Most procedures were elective (91.23%), primarily involving the abdominal and ‎groin regions. The average time required for wound closure was 7.77 ± 2.13 minutes. ‎The postoperative complications remained low throughout the study period, with 8.77% at ‎discharge, 1.75% at 2 months, and no complications at 12 months. Surgical site infections, ‎together with serious adverse events, did not occur throughout the study.‎

    Conclusion: The results showed that PINION™ PDO knotless sutures provided high safety ‎levels, easy handling, and efficient procedural performance. The study findings demonstrate ‎that this material may function as a suitable replacement for traditional sutures in ‎typical surgical procedures‎.

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  • How to Cite

    Patel, A. K., Trivedi, J. ., Patel, H. ., Parmar , S. N. ., Shah , J. ‎, & Shetty, K. K. . (2026). Real-World Evaluation of Dual-Axis Barbed PDOKnotless Sutures in Elective Soft ‎Tissue Closure:A Multicenter Observational Study. International Journal of Basic and Applied Sciences, 15(2), 15-21. https://doi.org/10.14419/dmr9kg13