Effect of Matrix Rhythm Therapy Along with Wall Squats and Conventional Therapy in Individuals with Osteoarthritis of Knee: A ‎Randomized Controlled Trial

  • Authors

    • Pramod Palekar Associate Professor, Department of Electrotherapy, Dr. D. Y. Patil College of Physiotherapy, Dr. D.Y. Patil Vidyapeeth, Pimpri, Pune, Maha-‎rashtra, India
    • Tushar Palekar Professor & Principal, Department of Musculoskeletal Sciences, Dr. D.Y. Patil College of Physiotherapy, Dr. D. Y. Patil Vidyapeeth, Pimpri, Pune, ‎Maharashtra, India
    • Purva Deshmukh Intern, Dr. D.Y. Patil College of Physiotherapy, Dr. D. Y. Patil Vidyapeeth, Pimpri, Pune, Maharashtra, India
    • Gaurang Baxi Associate Professor, Institute of Medical Education Technology and Teachers' Training, MUHS Nashik, Maharashtra, India
    • Om Wadhokar Assistant Professor, Department of Musculoskeletal Sciences, Dr. D.Y. Patil College of Physiotherapy, Dr. D. Y. Patil Vidyapeeth, Pimpri, Pune, ‎Maharashtra, India
    https://doi.org/10.14419/mmypve33

    Received date: August 3, 2025

    Accepted date: August 9, 2025

    Published date: August 25, 2025

  • Knee Osteoarthritis; Matrix Rhythm Therapy; Physiotherapy; Rehabilitation.

  • Abstract

    Background: Knee osteoarthritis (OA) is a progressive degenerative condition that causes pain, restricted mobility, and reduced quality of life. ‎Standard physiotherapy may not always address both tissue-level dysfunction and biomechanical deficits. Matrix Rhythm Therapy (MRT) is a novel ‎modality that uses low-frequency mechanical vibrations to improve microcirculation, tissue relaxation, and oxygen delivery. This study evaluated the ‎combined effects of MRT, wall squats, and conventional exercises in patients with unilateral knee OA.‎

    Methods: An interventional study was conducted at Dr. D.Y. Patil College of Physiotherapy OPD. Thirty participants aged 45–65 years, diagnosed ‎with unilateral knee OA (NPRS 5–8), were randomly allocated into two groups (n=15 each). Group 1 received MRT with wall squats and conven-‎tional exercises; Group 2 received MRT with conventional exercises only. Interventions were administered for 10 sessions over two weeks. Outcomes ‎measured pre- and post-intervention included pain (Numerical Pain Rating Scale, NPRS), knee range of motion (ROM), and functional performance ‎‎(Knee injury and Osteoarthritis Outcome Score, KOOS).‎

    Results: Within-group analysis showed significant improvements in pain, knee flexion ROM, and KOOS scores in both groups (p<0.05), with no ‎significant change in knee extension ROM. Between-group comparison indicated Group 1 achieved significantly greater pain reduction (p=0.025) ‎and showed a trend toward greater improvement in knee flexion ROM and KOOS scores, though differences were not statistically significant.‎

    Conclusion: The integration of MRT, wall squats, and conventional exercises is effective in reducing pain and improving functional performance in ‎knee OA, offering a holistic, non-invasive rehabilitation approach‎.

  • References

    1. Abbassy AA, Trebinjac S, Kotb N. The use of cellular matrix in symptomatic knee osteoarthritis. Bosn J Basic Med Sci. 2020 May 1;20(2):271–4. https://doi.org/10.17305/bjbms.2019.4205.
    2. Warutkar VB, Samal S, Zade RJ. Matrix Rhythm Therapy (MRT) Along with Conventional Physiotherapy Proves to Be Beneficial in a Patient With Post-Operative Knee Stiffness in Case of Tibia-Fibula Fracture: A Case Report. Cureus. 2023 Sep;15(9):e45384. https://doi.org/10.7759/cureus.45384.
    3. Maiya GA, Jadhav RA, Harihar A, Gundmi S, Shetty AG, Yadav K H, et al. Effect of novel Matrix Rhythm Therapy (MaRhyThe®) on neuro-pathic pain and maximum plantar pressure distribution among type 2 diabetes mellitus patients with peripheral neuropathy. J Diabetes MetabDisord. 2023 Jun;22(1):827–33. https://doi.org/10.1007/s40200-023-01210-8.
    4. Unal A, Altug F, Tikac G, Cavlak U. Effectiveness of matrix-rhythm therapy on increased muscle tone, balance and gait parameters in stroke survi-vors: a single-blinded, randomized, controlled clinical trial. Acta Neurol Belg. 2021 Jun;121(3):689–99. https://doi.org/10.1007/s13760-020-01391-6.
    5. Özcan NT, Çalık BB, Kabul EG. The Effectiveness of Matrix Rhythm Therapy in Patients with Chronic Low Back Pain. Spine. 2021 Jun 15;46(12):781–7. https://doi.org/10.1097/BRS.0000000000003898.
    6. Tore NG, Oskay D, Haznedaroglu S. The quality of physiotherapy and rehabilitation program and the effect of telerehabilitation on patients with knee osteoarthritis. Clin Rheumatol. 2023 Mar;42(3):903–15. https://doi.org/10.1007/s10067-022-06417-3.
    7. Gurjalwar I, Kalaskar G, Phansopkar P, Shah P, Chitale N, Wadhokar OC. Impact of a retro walking on degenerative osteoarthritis of knee joint. 11(2320).
    8. Joshi MV, Kulkarni CA, Wadhokar OC, Wanjari MB. Growing Trends in Scientific Publication in Physiotherapy Treatment of Knee Osteoarthritis: A Bibliometric Literature Analysis. Cureus. 2023 Nov;15(11):e48292. https://doi.org/10.7759/cureus.48292.
    9. Bhakaney PR, Wadhokar OC, Upase S. Matrix Rhythm Therapy as a Novel Clinical Approach in the Rehabilitation of Surgically Treated Distal Radius Fracture: A Single Case Study. Cureus. 2024;16(2). https://doi.org/10.7759/cureus.54785.
    10. Bhatikar DK. EFFECT OF MATRIX RHYTHM THERAPY AND FACIAL NEUROMUSCULAR RETRAINING PROGRAM IN BELL’S PALSY: CASE REPORT. :4.
    11. Ovid [Internet]. [cited 2025 Aug 8]. Effect of Matrix Rhythm Therapy in Individuals... : Journal of Datta Meghe Institute of Medical Sciences University. Available from: https://www.ovid.com/journals/dmms/fulltext/10.4103/jdmimsu.jdmimsu_679_23~effect-of-matrix-rhythm-therapy-in-individuals-with.
    12. Sangaonkar M, Baxi G, Wadhokar O, Kharat A, Palekar TJ, Sonpatki M, et al. Effect of Matrix Rhythm Therapy on adhesive capsulitis of shoul-der: A case report. Med Sci. 2023;27:e386ms3102. https://doi.org/10.54905/disssi.v27i142.e386ms3102.
    13. Sangaonkar M, Baxi GD, Bhakaney PR, Palekar TJ, Kuber RS. Exploring Coracohumeral Ligament Elasticity Changes With Matrix Rhythm Ther-apy in Idiopathic Adhesive Capsulitis: A Case Report. Cureus. 2024 Aug;16(8):e66608. https://doi.org/10.7759/cureus.66608.
    14. Gohil D, Kathed RS, Palekar TJ. Cracking the Code of Digital Discomfort Through the Dynamic Fusion of Matrix Rhythm Therapy and Physio-therapy Exercises for Text Neck Syndrome. Cureus. 2024 Apr;16(4):e58085. https://doi.org/10.7759/cureus.58085.
    15. Escamilla RF, Zheng N, Macleod TD, Edwards WB, Imamura R, Hreljac A, et al. Patellofemoral joint force and stress during the wall squat and one-leg squat. Med Sci Sports Exerc. 2009 Apr;41(4):879–88. https://doi.org/10.1249/MSS.0b013e31818e7ead.
    16. Rachel. Functional exercise versus conventional exercise [Internet]. QSP Physiotherapy & Massage. 2021 [cited 2025 Aug 8]. Available from: https://qsp.physio/functional-exercise-versus-conventional-exercise/.

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  • How to Cite

    Palekar, P., Palekar, T. ., Deshmukh, P., Baxi, G., & Wadhokar, O. (2025). Effect of Matrix Rhythm Therapy Along with Wall Squats and Conventional Therapy in Individuals with Osteoarthritis of Knee: A ‎Randomized Controlled Trial. International Journal of Basic and Applied Sciences, 14(4), 641-647. https://doi.org/10.14419/mmypve33