Nursing Strategies and Safety Devices for Preventing Parenteral Therapy–‎Related Iatrogenesis in Low- And Middle-Income Countries: A Scoping Review

Authors

  • Qudus Bayonle Olayiwola Department of Public Health/Community Health Nursing, Ladoke Akintola University of ‎Technology, Ogbomoso, Nigeria https://orcid.org/0009-0003-4254-4161 (unauthenticated)
  • Hazanah Adebola Suleiman Department of Public Health/Community Health Nursing, Ladoke Akintola University of ‎Technology, Ogbomoso, Nigeria https://orcid.org/0009-0009-8275-1740 (unauthenticated)
  • Ogooluwa Joshua Agboola olayiwolaqudus2504@gmail.comDepartment of Public Health/Community Health Nursing, Ladoke Akintola University of ‎Technology, Ogbomoso, Nigeria https://orcid.org/0009-0002-9869-5631 (unauthenticated)
  • Mubarak Ademola Egbinola Department of Public Health/Community Health Nursing, Ladoke Akintola University of ‎Technology, Ogbomoso, Nigeria https://orcid.org/0009-0000-1726-5863 (unauthenticated)
  • Zainab Moyosore Ayanwale Department of Public Health/Community Health Nursing, Ladoke Akintola University of ‎Technology, Ogbomoso, Nigeria https://orcid.org/0009-0009-5120-762X (unauthenticated)
  • Nurudeen Ajadi Gbamigbola College of Medicine, University of Ibadan, Ibadan, Nigeria https://orcid.org/0009-0006-2482-9181 (unauthenticated)
  • Rukayat Ebudola Fatai Department of Nursing, Obafemi Awolowo University, Ile-Ife, Osun, Nigeria
  • Oluwatobi ‎Deborah Ayodeji Department of Public Health/Community Health Nursing, Ladoke Akintola University of ‎Technology, Ogbomoso, Nigeria
  • Praise Olatide Oki Department of Public Health/Community Health Nursing, Ladoke Akintola University of ‎Technology, Ogbomoso, Nigeria
  • Olamide Arkofgod Oki Department of Public Health/Community Health Nursing, Ladoke Akintola University of ‎Technology, Ogbomoso, Nigeria
  • Demilade Sarah Olaniyi Department of Public Health/Community Health Nursing, Adeleke University, Nigeria

DOI:

https://doi.org/10.14419/dz8dbw05

Published

14-06-2026

Keywords:

Parenteral Therapy; Medication Safety; Nursing Practice; Safety Devices; Low- and Middle-Income ‎Countries

Abstract

Background: Parenteral therapy is a high-risk component of clinical care because injectable and ‎infused medicines bypass physiological barriers, enabling rapid harm when errors occur. In low- ‎and middle-income countries [LMICs], these risks may be intensified by staffing constraints, ‎limited device availability, weak reporting systems, and inconsistent infection prevention ‎infrastructure.‎

Objective: This scoping review mapped evidence on parenteral therapy–related iatrogenic risks, ‎safety devices, and medication administration technologies, and nursing and system-level ‎determinants of safer parenteral therapy implementation in LMICs.‎

Methods: A scoping review was conducted in accordance with PRISMA-ScR guidance. ‎PubMed/MEDLINE, Scopus, Web of Science, and CINAHL were searched for English-language ‎publications from 2010 to 2026. Additional sources were identified through citation searching, ‎professional guidance, and relevant reference lists. 71 studies met the inclusion criteria; 68 were ‎mapped to one or more review objectives, while 3 studies supported methodological, conceptual, ‎or background framing. Evidence was synthesized using narrative synthesis and evidence ‎mapping, guided by the SEIPS socio-technical systems framework.‎

Results: The review found that Iatrogenesis spanned all clinical phases, including preparation ‎errors, glass particulate contamination, wrong infusion rates, catheter-related infections, and unsafe ‎injection practices. These risks were exacerbated by heavy workloads and workflow interruptions. ‎Safety devices addressed specific vulnerabilities: prefilled syringes reduced preparation complexity; ‎filters mitigated particulate exposure; smart pumps reduced programming errors; and ‎BCMA/eMAR systems strengthened verification. However, technology effectiveness depended on ‎training, usability, workflow integration, procurement reliability, and institutional support.‎

Conclusion: Preventing parenteral therapy–related iatrogenesis in LMICs requires layered, ‎context-sensitive implementation combining nursing competence, standardized protocols, robust ‎infection prevention, safety devices, and organizational governance.

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How to Cite

Olayiwola, Q. B., Suleiman, H. A., Agboola, O. J., Egbinola, M. A., Ayanwale, Z. M., Gbamigbola, N. A., Fatai, R. E., Ayodeji, O. ‎Deborah, Oki, P. O., Oki, O. A., & Olaniyi, D. S. (2026). Nursing Strategies and Safety Devices for Preventing Parenteral Therapy–‎Related Iatrogenesis in Low- And Middle-Income Countries: A Scoping Review. International Journal of Advanced Nursing Studies, 14(1), 8-24. https://doi.org/10.14419/dz8dbw05

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