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Authors

  • L. H. Nkasa Université de Kinshasa
  • M. C. Mulenga Université de Kinshasa
  • M. J. Muzomwe Université de Kinshasa
  • S. J. Kayembe Université de Kinshasa
  • L. B. Ilinga Université de Kinshasa
  • M. Z. Kashongwe Université de Kinshasa
  • B. P. Ngoy Université de Kinshasa
  • K. M Taba Université de Kinshasa

DOI:

https://doi.org/10.14419/ijet.v11i1.32057

Published:

2022-06-07

Keywords:

Mycobacterium Ulcerans, Mycolactone, Γ-Butyrolactone, Buruli Ulcer, Mathesia.

Abstract

Kinetic studies of the interaction between  Î³-Butyrolactone and one of the phytomedecines such as Mathesia used for Buruli ulcer treatment were investigated by conductimetry. γ-Butyrolactone which is the simplest form of lactone was used as probe in order to fully understand how a cyclic ester, such as lactone, could behave in a basic environment. It was observed that for the Mathesia solution at pH 11 the minimal apparent rate constant was around 3.54636 compare to sodium hydroxyde solution at pH 12 where the minimal apparent rate constant was around 3.12295. The apparent rate constants of successive diluted solutions of Phytomedicine Mathesia show up the dilution factor 1: 4. A plot of apparent rate constant versus dilution factor gave a curve with a correlation coefficient of 0.99831.

 

 

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How to Cite

H. Nkasa, L., C. Mulenga, M., J. Muzomwe, M., J. Kayembe, S., B. Ilinga, L., Z. Kashongwe, M., P. Ngoy, B., & M Taba, K. (2022). Dear Author, We are sorry to tell you that we cant open your submission file ; we think it was corrupted while submission process Please submit your paper again . Note: we will remove your submission from our editorial system and waiting for your new. International Journal of Engineering & Technology, 11(1), 73–77. https://doi.org/10.14419/ijet.v11i1.32057
Received 2022-04-25
Accepted 2022-05-16
Published 2022-06-07