Effect of Robusta Coffee to Multiple Organ Histopathological Change on Rats Strain Wistar

  • Authors

    • Dian Y. Lestari
    • M. Aleq Sander
    • Halida Nelasari
    • Anung P. Ilahika
    • Saidah Rahmat
    • Meta Sophia
    • Deby Rahman
    https://doi.org/10.14419/ijet.v8i1.9.30090
  • Robusta coffee, Morphological change.

  • Coffee beans as beverages that contains acrylamide that formed in roasted process. Acrylamide can make multiple organ dysfunction on rats. The atudy aims to prove the effect of Robusta on Morphological changes of Hepatocytes, colonic mucosa, and prostatic acinar on Male rats . True experimental post test only control group design. 24 samples of male rats clustered in 5 groups; control group and treatment group were given steeping doses of coffee (0.36ml, 0.72ml, 1.44ml, and 2.16ml). Analysis of the data using One-Way ANOVA showed that there are significant value 0.000. Steeping of robusta coffee (Coffea canephora var. Robusta) could cause morphological changes of hepatocytes cell, colonic mucosa, and prostatic acinar in male rats (Rattus novergicus Strain Wistar).

     

     

  • References

    1. [1] Bhara M. 2009. The effect of steeping coffee to hepatic histological picture on rats. Diponegoro University. Semarang. P1-2.

      [2] Harahap, Y. 2006. The analysis dan formation of acrylamide on food. Majalah Ilmu Kefarmasian. Vol 3(3):107-112.

      [3] Robbins. 2014. Basic pathology of disease. 8th edition. Elsevier. P64-78.

      [4] Tanseri. 2010. The effect of temperature on levels acrylamide. Sumatra University. Medan. P 5-9

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  • How to Cite

    Y. Lestari, D., Aleq Sander, M., Nelasari, H., P. Ilahika, A., Rahmat, S., Sophia, M., & Rahman, D. (2019). Effect of Robusta Coffee to Multiple Organ Histopathological Change on Rats Strain Wistar. International Journal of Engineering & Technology, 8(1.9), 698-700. https://doi.org/10.14419/ijet.v8i1.9.30090