Application of Image Processing in Adaptation of Yeast to Environmental Conditions, Optimized by Autogegulatory Molecules and PSO

  • Abstract
  • Keywords
  • References
  • PDF
  • Abstract

    Unlike bacterial signal molecules, secreted yeast ones, which ensure their coordinated behavior as a single system, have been little studied. We used the image processing technique to evaluate the environmental conditions. Communication through quorum sensing molecules (QSM) is the dominant signaling in prokaryotic populations. In eukaryotic yeast cells, stress, caused primarily by the nutrient limit, causes a phenotypic manifestation of the mechanism of dimorphic switching, encompassing the repression of certain groups of genes and the activation of others, determining adhesion and virulence. Analysis of literature data and the results of the authors' own research emphasize the importance of signaling studies involving autoinducer molecules to elucidate the fundamental laws governing the regulation of yeast physiology, including growth parameters, morphogenesis and pathogenicity.



  • Keywords

    Image processing, quorum sensing, Medical engineering, yeast, particle swamp optimization

  • References

      [1] C.N. LaRock, J. Yu, A.R. Horswill et al. “Transcriptome analysis of acetyl-homoserine lactone-based quorum sensing regulation in Yersinia pestis”, PloS One, 2013, vol. 8, № 4, pp. e62337.

      [2] G.I. El-Registan, A.L. Mulyukin, Yu.A. Nikolaev et al. Adaptogenic functions of extracellular autoregulators of microorganisms. Microbiology (Mikrobiologiya), 2006, vol. 75, № 4, pp. 380-389.

      [3] G.F. Sprague, S.C. Winans “Eukaryotes learn how to count: quorum sensing by yeast”, Genes & development, 2006, vol. 20, № 9, pp. 1045-1049.

      [4] H. Chen, M. Fujita, Q. Feng et al. “Tyrosol is a quorum-sensing molecule in C. albicans”, PNAS, 2004, vol. 101, № 14, pp. 5048-5052.

      [5] H. Chen, G.R. Fink “Feedback control of morphogenesis in fungi by aromatic alcohols”, Genes & development, 2006, vol. 20, № 9, pp. 1150-1161.

      [6] M. Kruppa “Quorum sensing and C. albicans”, Mycoses, 2009, vol. 52, № 1, pp. 1-10.

      [7] P. Albuquerque, A. Casadevall “Quorum sensing in fungi–a review”, Medical mycology, 2012, vol. 50, № 4, pp. 337-345.

      [8] S.M. Honigberg “Cell signals, cell contacts, and the organization of yeast communities”, Eukaryotic cell, 2011, vol. 10, № 4, pp. 466-473.

      [9] J. Perlroth, B. Choi, B. Spellberg “Nosocomial fungal infections: epidemiology, diagnosis, and treatment”, Medical mycology, 2007, vol. 45, № 4, pp. 321-346.

      [10] M.A. Pfaller, D.J. Diekema “Epidemiology of invasive candidiasis: a persistent public health problem”, Clinical microbiology reviews, 2007, vol. 20, №. 1, pp. 133-163.

      [11] M. Stratford “Food and beverage spoilage yeasts. Yeasts in food and beverages”, Berlin, 2006, pp. 335-379.

      [12] J. Kurjan “The pheromone response pathway in S. cerevisiae”, Annual review of genetics, 1993, vol. 27, № 1, pp. 147-179.

      [13] W.L. Ng, B.L. Bassler “Bacterial quorum-sensing network architectures”, Annual review of genetics, 2009, vol. 43, pp. 197-222.

      [14] J.J. Walker, N.R. Pace “Endolithic microbial ecosystems”, Annu. Revol. Microbiol, 2007, vol.61, pp. 331-347.

      [15] D.A. Hogan “Talking to themselves: autoregulation and quorum sensing in fungi”, Eukaryotic cell, 2006, vol. 5, № 4, pp. 613-619.

      [16] J.M. Hornby, E.C. Jensen, A.D. Lisec et al. “Quorum sensing in the dimorphic fungus Candida albicans is mediated by farnesol”, Applied and environmental microbiology, 2001, vol. 67, № 7, pp. 2982-2992.

      [17] J. Zupan, M. Avbelj, B. Butinar et al. “Monitoring of quorum-sensing molecules during minifermentation studies in wine yeast”, J of agricultural and food chemistry, 2013, vol. 61, № 10, pp. 2496-2505.

      [18] M. Avbelj, J. Zupan, L. Kranjc, P. Raspor “Quorum-sensing kinetics in S. cerevisiae: a symphony of ARO genes and aromatic alcohols”, J of agricultural and food chemistry, 2015, vol. 63, № 38, pp. 8544-8550.

      [19] I.M.H. Rijswijck, J. Dijksterhuis, J.C.M. Wolkers-Rooijackers et al. “Nutrient limitation leads to penetrative growth into agar and affects aroma formation in Pichia fabianii, P. kudriavzevii and S. cerevisiae”, Yeast, 2015, vol. 32, № 1, pp. 89-101.

      [20] Z Palkova, L. Vachova “Ammonia signaling in yeast colony formation”, International review of cytology, 2003, vol. 225, pp. 229-272.

      [21] L. Vachova, Z. Palková “Physiological regulation of yeast cell death in multicellular colonies is triggered by ammonia”, The Journal of cell biology, 2005, vol. 169, № 5, pp. 711-717.

      [22] K.J. Verstrepen, G.R. Fink “Genetic and epigenetic mechanisms underlying cell-surface variability in protozoa and fungi”, Annual review of genetics, 2009, vol. 43, pp. 1-24.

      [23] R.K. Bojsen, K.S. Andersen, B. Regenberg “S. cerevisiae – a model to uncover molecular mechanisms for yeast biofilm biology”, FEMS Immunology & Medical Microbiology, 2012, vol. 65, № 2, pp. 169-182.

      [24] R.R. Barrales, J. Jimenez, J.I. Ibeas “Identification of novel activation mechanisms for FLO11 regulation in S. cerevisiae”, Genetics, 2008, vol. 178, № 1, pp. 145-156.

      [25] M. Fidalgo, R.R. Barrales, J.I. Ibeas, J. Jimenez “Adaptive evolution by mutations in the FLO11 gene”, Proceedings of the National Academy of Sciences, 2006, vol. 103, № 30, pp. 11228-11233.

      [26] X Pan, J. Heitman “Protein kinase A operates a molecular switch that governs yeast pseudohyphal differentiation”, Molecular and cellular biology, 2002, vol. 22, № 12, pp. 3981-3993.

      [27] A.B. Margulis, E.T. Gilyazova, F.G. Kuprianova-Ashina. Growth peculiarities of the C. tropicalis and S. cerevisiae culture in the presence of furanone. Advances in Medical Mycology, 2013, vol. 11, № 9, pp. 326-329. (In Russian).

      [28] E.T. Kalimullina, A.B. Margulis, A.I. Kolpakov, F.G. Kuprianova-Ashina Growth peculiarities of the S. cerevisiae culture in the presence of exogenous autoregulators of the cell population density. Uchenye Zapiski Kazanskogo Universiteta. Seriya Estestvennye Nauki, 2015, vol. 157, № 4, pp. 27-38. (In Russian).

      [29] K. Winzer, K.R. Hardie, P. Williams “Bacterial cell-to-cell communication: sorry, can't talk now - gone to lunch!”, Current opinion in microbiology, 2002, vol. 5, № 2, pp. 216-222.

      [30] S. Raina D. De Vizio, M. Odell “Microbial quorum sensing: a tool or a target for antimicrobial therapy”, Biotechnology and applied biochemistry, 2009, vol. 54, № 2, pp. 65-84.

      [31] K.L. Visick, C. Fuqua “Decoding microbial chatter: cell-cell communication in bacteria”, J of bacteriology, 2005, vol. 187, № 16, pp. 5507-5519.

      [32] E.T. Kalimullina, A.A. Bayazitova, I.S. Nizamov, A.I. Kolpakov, F.G. Kupriyanova-Ashina, O.N. Ilyinskaya “Impact of exogenous autoregulators of intercellular communication in yeast on the growth of S. cerevisiae”, International J of Pharmacy & Technology, 2016, vol. 8, № 4, pp. 24496-24507.

      [33] K.J. Boyce, A. Andrianopoulos “Fungal dimorphism: the switch from hyphae to yeast is a specialized morphogenetic adaptation allowing colonization of a host”, FEMS microbiology reviews, 2015, vol. 39, № 6, pp. 797-811.




Article ID: 20344
DOI: 10.14419/ijet.v7i4.7.20344

Copyright © 2012-2015 Science Publishing Corporation Inc. All rights reserved.