Synthesis and Spectral Studies of Novel Palladium (O) Complex with Ciprofloxacin Antibiotic
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https://doi.org/10.14419/ijet.v7i4.36.24230
Received date: December 18, 2018
Accepted date: December 18, 2018
Published date: December 9, 2018
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Spectral studies, palladium complex, ciprofloxacin, elemental analysis. -
Abstract
New complex of Palladium (0) with ciprofloxacin has been synthesized, The complex was portrayed by different physico - substance systems like essential examination, m.pt. , TLC, molar conductance estimation, attractive helplessness,13C- NMR, 1H-NMR and FT-IR. According to the results obtained, tetrahedral structure suggested for the prepared complex. The neutral ligand act in a Didentate mode, binding through oxygen atom of carbonyl group in pyridonering and oxygen atom of carboxyl ate group.
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References
- Mertindale W, Martindale – the extra Pharmacopeia, 30thed, the Pharmaceutical Press, London, (1993).
- Turel I, Golobič A, Klavžar A, Pihlar B, Buglyo P, Tolis E & Sepčić K, “Interactions of oxovanadium (IV) and the quinolone family member—ciprofloxacin”, Journal of inorganic biochemistry, Vol.95, No.2, (2003), pp.199-207.
- Serafin A & Staczak A, “Russian Journal of Coordination Chemistry”, Springer, Vol.35, No.2, (2009), pp.83-97.
- Anacona JR & Toledo C, “Synthesis and antibacterial activity of metal complexes of ciprofloxacin”, Transition Metal Chemistry, Vol.26, No.1-2, (2001), pp.228-231.
- Psomas G, “Mononuclear metal complexes with ciprofloxacin: synthesis, characterization and DNA-binding properties”, Journal of inorganic biochemistry, Vol.102, No.9, (2008), pp1798-1811.
- Delaney S, Pascaly M, Bhattacharya PK, Han K & Barton JK, “Oxidative damage by ruthenium complexes containing the dipyridophenazine ligand or its derivatives: a focus on intercalation”, Inorganic chemistry, Vol.41, No.7, (2002), pp.1966-1974.
- Kara M, Hasinoff BB, McKay DW & Campbell NR, “Clinical and chemical interactions between iron preparations and ciprofloxacin”, British journal of clinical pharmacology, Vol.31, No.3, (1991), pp.257-261.
- Ball P, “Quinolone generations: natural history or natural selection?”, Journal of Antimicrobial Chemotherapy, Vol.46, No.3, (2000), pp.17-24.
- Turel I, “The Interactions of metal ions with quinolone Antibacterial Agents”, Coordination Chemistry Reviews, Vol.232, No.1-2, (2002), pp.27-47.
- Vieira LMM, De Almeida MV, De Abreu HA, Duarte HA, Grazul RM & Fontes APS, “Platinum (II) complexes with fluoroquinolones: Synthesis and characterization of unusual metal–piperazine chelates”, Inorganica Chimica Acta, Vol.362, No.6, (2009), pp.2060-2064.
- Rusu A, Tóth G, Szőcs L, Kökösi J, Kraszni M, Gyéresi Á & Noszál B, “Triprotic site-specific acid–base equilibria and related properties of fluoroquinolone antibacterials”, Journal of pharmaceutical and biomedical analysis, Vol.66, (2012), pp.50-57.
- Siddiqi ZA, Khalid M, Kumar S, Shahid M & Noor S, “Antimicrobial and SOD activities of novel transition metal complexes of pyridine-2, 6-dicarboxylic acid containing 4-picoline as auxiliary ligand”, European journal of medicinal chemistry, Vol.45, No.1, (2010), pp.264-269.
- Liu YC, Chen ZF, Shi SM, Luo HS, Zhong DC, Zou HL & Liang H, “Synthesis, crystal structure of polyoxovanadate complex of ciprofloxacin: V4O10(μ2-O)2 [VO(H-Ciprof)2]2·13H2O by hydrothermal reaction”, Inorganic Chemistry Communications, Vol.10, No.11, (2007), pp.1269-1272.
- Negishi E, Handbook of Organ palladium Chemistry for Organic Synthesis, Wiley-Inter science: New York, (2002).
- Tsuji J, Palladium in Organic Synthesis, Springer: Berlin, (2005).
- Li J & Gribble GW, Palladium in Heterocyclic Chemistry, Pergamon: New York, (2000).
- Jafar NN & Majeed NS, “Microwave-assisted synthesis and biological activity of ester, carbothioate and carbohydrazide derivative compounds of the drug Ciprofloxacin”, J. Chem. Pharmaceut. Sci., Vol.10, (2017), pp.515-521.
- Nakamoto K, Infrared spectra of inorganic and coordination compounds. 2nded. New York: Wiley Inter science, (1970).
- Ferraro JR, Low frequency vibrations of inorganic and coordination compounds. 2nded. New York: John Wiley, (1971).
- Kothari R, Sharma B, Sahawal S, Neha K, Mandal S, Birthare S & Shivhare V, “Synthesis, Characterization And Antimicrobial Evaluation of Copper (Ii) Complex with Ciprofloxacin Antibiotic”, World Journal of Pharmacy and Pharmaceutical Sciences, Vol.4, No.6, (2015), pp.696-707.
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How to Cite
S. Majeed, N., K. Kareem, I., & N.A. Jafar, N. (2018). Synthesis and Spectral Studies of Novel Palladium (O) Complex with Ciprofloxacin Antibiotic. International Journal of Engineering and Technology, 7(4.36), 722-724. https://doi.org/10.14419/ijet.v7i4.36.24230
