Proposal of an international harmonized analytical technique for quantifying of residual acetamiprid and imidacloprid in wheat

  • Authors

    • Naoto Furusawa Graduate School of Human Life Science, Osaka City University
    2015-01-20
    https://doi.org/10.14419/ijac.v3i1.4015
  • International Harmonized Analytical Method, Acetamiprid, Imidacloprid, Centrifugal Monolithic Silica Spin Mini-Column.

  • This paper proposes an international harmonized analytical method for residual monitoring of selected neonicotinoids in crops and presents a fast, easy, and space-saving technique of sample preparation followed by a 100% water mobile phase high-performance liquid chromatography (HPLC) coupled photo-diode array detector (PDA) for quantifying acetamiprid (ATP) and imidacloprid (ICP) in wheat. The analytes were extracted from the sample using a handheld ultrasonic homogenizer with water, and purified by MonoSpin® C18-CX, a centrifugal monolithic silica spin mini-column, and quantified within 20 min/sample. The accuracy, precision, and system suitability are well within the international method acceptance criteria.

  • References

    1. [1] Cressey D (2013) "Europe debates risk to bees", Nature 496, 408. http://dx.doi.org/10.1038/496408a.

      [2] European Commission, Regulation (EU) No 485/2013, 2013. http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2013:139:0012:0026:EN:PDF .

      [3] European Commission, Bees & Pesticides: Commission goes ahead with plan to better protect bees. 30 May 2013. http://ec.europa.eu/food/archive/animal/liveanimals/bees/neonicotinoids_en.htm .

      [4] European Food Safety Authority (EFSA), EFSA assesses po-tential link between two neonicotinoids and developmental neurotoxicity. Press release 17 December 2013. http://www.efsa.europa.eu/en/press/news/131217.htm .

      [5] FAO, FAOSTAT, Retrieved 23 November 2013. http://faostat3.fao.org/browse/Q/*/E .

      [6] Codex Alimentarius, Pesticide Residues in Food and Feed, Codex Pesticides Residues in Food Online Database 2013.

      [7] Chen M, et al (2013) Simultaneous determination of residues in pollen and high-fructose corn syrup from eight neonicotinoid insecticides by liquid chromatography-tandem mass spectrometry. Anal. Bioanal. Chem. 405, 9251-9264. http://dx.doi.org/10.1007/s00216-013-7338-7.

      [8] Xiao Z, et al. (2013) Determination of neonicotinoid insecticides residues in eels using subcritical water extraction and ultra-performance liquid chromatography-tandem mass spectrometry. Anal. Chim. Acta 777, 32-40. http://dx.doi.org/10.1016/j.aca.2013.03.026.

      [9] Jovanov P, et al. (2013) Multi-residue method for determination of selected neonicotinoid insecticides in honey using optimized dispersive liquid-liquid microextraction combined with liquid chromatography-tandem mass spectrometry. Talanta 111, 125-133. http://dx.doi.org/10.1016/j.talanta.2013.02.059.

      [10] Xie W, et al. (2011) Determination of neonicotinoid pesticides residues in agricultural samples by solid-phase extraction combined with liquid chromatography-tandem mass spectrometry. J. Chromatogr. A 1218, 4426-4433. http://dx.doi.org/10.1016/j.chroma.2011.05.026.

      [11] Seccia S, et al. (2008) Determination of neonicotinoid insecticides residues in bovine milk samples by solid-phase extraction clean-up and liquid chromatography with diode-array detection. J. Chromatogr. A 1214, 115-120. http://dx.doi.org/10.1016/j.chroma.2008.10.088.

      [12] Di Muccio A, et al. (2006) Application of solid-phase extraction and liquid chromatography-mass spectrometry to the determination of neonicotinoid pesticide residues in fruit and vegetables. J. Chromatogr. An 1108, 1-6. http://dx.doi.org/10.1016/j.chroma.2005.12.111.

      [13] Ferrer I, et al. (2005) Quantitation and accurate mass analysis of pesticides in vegetables by LC/TOF-MS. Anal. Chem. 77, 2818-2825. http://dx.doi.org/10.1021/ac048458x.

      [14] EU classification (The Dangerous Substances Directive 67/548/EEC): Council Directive 67/548/EEC of 27 June 1967 on the approximation of laws, regulations and administrative provisions relating to the classification, packaging and labelling of dangerous substances.

      [15] Anastas, PT, and Warner, JC, Green Chemistry: Theory and Practice; Oxford University Press: Oxford, United Kingdom (1998).

      [16] Yoshimura, T, et al., Green Chemistry: Aim for the Zero Emission-Chemicals, Sankyo Publishing Co. Ltd. Press, Tokyo, Japan (2001).

      [17] FDA/CDER/CVM, Guidelines for Industry – Bioanalytical Method Validation, 2001. http://www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/Guidances/UCM070107.pdf .

      [18] FDA, Reviewer Guide, Validation of Chromatographic Method Center Drug Evaluation and Research (CFDER), Silver Spring, MD, USA, 1994.

      [19] Huber, L, Validation and Quantification in Analytical Laboratories, Interpharm Press, East England, CO, USA, 1998.

      [20] ICH, Work Products, ICH Guidelines, Quality Guidelines- Validation of analytical procedures: Test and methodology Q2 (R1), 1994. http://www.ich.org/products/guidelines.html .

      [21] AOAC International, Guidelines for Standard Method Performance Requirements, 2012. http://www.eoma.aoac.org/app_f.pdf .

      [22] Codex alimentarius commission, ALINORM 01/23, Codex Committee on Methods of Analysis and Sampling, Joint FAO/WHO Food Standards Programme, the 23nd Session of the Codex Committee on Method of Analysis and Sampling, March 2001.

      [23] GL Sciences, Monolithic SPE Column for the Purification and Enrichment of Small Amount Sample, MonoSpin® Series. http://www.glsciences.com/c-product/sample/solid/monospin-series/ .

  • Downloads

    Additional Files

  • How to Cite

    Furusawa, N. (2015). Proposal of an international harmonized analytical technique for quantifying of residual acetamiprid and imidacloprid in wheat. International Journal of Advanced Chemistry, 3(1), 14-17. https://doi.org/10.14419/ijac.v3i1.4015