Synthesis and characterization of iron (III) complexes of l-leucine and l-methionine

  • Authors

    • Shuaibu Musa AHMADU BELLO UNIVERSITY, Zaria
    • Iyun J F AHMADU BELLO UNIVERSITY
    • Shuaibu Musa Abubakar AHMADU BELLO UNIVERSITY,ZARIA
    2019-05-27
    https://doi.org/10.14419/ijac.v7i1.16098
  • L-Leucine, L-Methionine, Chelation, Electrolytic and Complexes.
  • The resulted complexes produced between Fe (III) and biological molecules like amino acids play an important role in human life. Fe (III) complexes are synthesized with l-Leucine and l-Methionine. The complexes were characterized by elemental analysis (AAS), molar conductance, melting point, infrared and uv-visible spectrophotometry analyses. The elemental analyses were used to determine the chelation ratio, 1:3(metal: ligands). The molar conductivity of the complexes show that the complexes are not electrolytic in nature. Moreover, the melting point of the tris (l-Leucine) iron (III) and tris (l-Methionine) iron (III) are 2390C and 210oC respectively.

     

     

  • References

    1. [1] A.Stanila ,C.Nagag,A. Mercu, D.Cozma, D.Rusu, L.David,2008, Spectroscopic investigation of new metallic complexes with Leucine as ligands J. thermal Physics Elsevier pp.25-52.

      [2] Angela kriza, Lucica viorica, Nicoleta cioatera., 2010, Synthesis and structural studies of complexes of Cu, Co, Ni and Zn with isonicotinic acid hydrazide and isonicotinic acid (1-naphthylmethylene) hydrazide, J. Serb. Chem. Soc, 75 (2), 229-249. https://doi.org/10.2298/JSC1002229K.

      [3] Bellamy, L.J., 1966. The Infrared Spectra of Complex Molecules. Methuen, 3rd. ed., London, p 95.

      [4] Berg, J.L. Tymoczko, L. Stryer, 2001, Biochemistry, (fifth ed.), W.H. Freeman and Company, New York p. 41.

      [5] Barger, G.; Weichselbaum, T. E. 1934, "dl-Methionine", Org. Synth. 14: 58; Coll. Vol. 2: 384 https://doi.org/10.15227/orgsyn.014.0058.

      [6] Barger, G., and T. E. Weichselbaum. 1943. dl-methionine Organic Syntheses, vol. 2, pp. 384.

      [7] Geary, W.J., 1971. Use of Conductivity Measurements in Organic Solvents for the Characterization of Coordination Compounds, Coord. Chem. Rev., Vol.3, pp.81-122. https://doi.org/10.1016/S0010-8545(00)80009-0.

      [8] G.Socrates, “Infrared and raman characteristics frequencies; table and chart.third ed.wiley, chichester, 2001.

      [9] Gillam, Strem, E.S., 1957. An Introduction to Electronic Absorption Spectroscopy in Organic Chemistry. Arnold, London.

      [10] Geary W. J., 1971: The use of conductivity measurements in organic solvents for the characterisation of coordination compounds. Coord. Chem. Rev., 7:81. https://doi.org/10.1016/S0010-8545(00)80009-0.

      [11] Hugnes, M.N., 1981. The Inorganic Chemistry of Biological Processes. John Wiley and Sons,

      [12] Jatte, H.H., Orchin, M., 1962. Theory and Applications of Ultraviolet Spectroscopy. John Wiley and Sons, New York.

      [13] Liang, Y., Su, B., Zhao, J. and Sun, W., 2005. The Synthesis of New Asymmetric Double Schiff Bases Containing A New O-Amino Benzoic Acid Derivative, Synth. Commun., Vol. 34, No. 17, pp.3235-3242. https://doi.org/10.1081/SCC-200028639.

      [14] Longe, J. L., ed. 2005. The Gale Encyclopedia of Alternative Medicine. Detroit:Thomson/Gale

      [15] M.Q. Ehsan, S.Z. Haider, K.M.A. Malik, M.S. Khan, R.J., 1988, Quddus Dhaka Univ. Stud., 35 (2) pp. 153–160.

      [16] Moester, 1960, chemistry of the Amino Acids (second ed.), vol. 1 Academic Press Inc., New York, pp. 19–21

      [17] M.Q. Ehsan, K.M.A. Malik, S.Z. Haider J., 1996, Bangladesh Acad. Sci., pp. 175–181

      [18] M.N. Hugnes, 1981. The Inorganic Chemistry of Biological Processes John Wiley and Sons, New York

      [19] M.S. Rahman, H.M. Nasim Akter, P.K. Bakshi, M.Q. Ehsan J. 2007, Saudi Chem. Soc., pp. 277–286.

      [20] Moester, A., 1960, second ed. In: Biochemistry of the Amino Acids, vol. 1 Academic Press Inc., New York, pp. 19–21.

      [21] Nakamoto, K., 1988. IR and Raman Spectra of Inorganic and Coordination Compounds. Third ed. John Wiley and Sons, NY, p.211.

      [22] Nakamoto, K., 1978. Infrared and Raman Spectra of Inorganic and Coordinatio Compounds. John Wiley, 3rd ed., New York.

      [23] Nath, M. and Goyal, S., 2002. Synthesis, Characteristic Spectral Studies and in vitro Antimicrobial Activity of Organosilicon (IV) Complexes of N-(2-hydroxynaphthalidene) -Amino Acid Schiff Bases, Phosphorus, Sulfur, and Silicon and the Related Elements, Vol. 177, No. 2, pp. 447-463. https://doi.org/10.1080/10426500210250.

      [24] Panchai, P.K., Pansuriya, P.B. and Patel, M.N., 2006. In-vitro Biological Evaluation of Some ONS and NS Donor Schiff’s Bases and their Metal Complexes, J. Enzy. Inhib. Med. Chem., Vol. 21, No. 4, pp.453-458. https://doi.org/10.1080/14756360600628551.

      [25] Raman, N., Kulandaisamy, A. and Jeyasubramanian, K., 2001. Synthesis, Spectroscopic Characterization, Redox and Biological Screening Studies of Some Schiff Base Transition Metal (II) Complexes Derived from Salicylidene-4-Aminoantipyrine and 2-Aminophenol/2-Aminothiophenol, Synth. And React. in Inorg. Met. Org. and Nano-Met. Chem., Vol. 31, No. 7, pp.1249-1270. https://doi.org/10.1081/SIM-100106862.

      [26] Ranjana A, Xishi, T., Xian, H. Y., Qiang, C. and Minyu, T., (2003), “Synthesis of Some Transition Metal Complexes of a Novel Schiff Base Ligands Derived from 2, 2’ – Bis(p-Methoxy Phenylamine) and Salicylic Aldehydeâ€, Molecules, 8: 439-443. https://doi.org/10.3390/80500439.

      [27] Rai B.K., 2008, Synthesis, spectral and antimicrobial study of Co (II), Ni (II), Cu (II) complexes with Schiff bases of 3-pridinyl n-pentyl ketone, J. Ind. Council Chem., 25(2), 137-141.

      [28] Raman N., Pitchaikani Raja Y. and Kulandaisamy A., 2001, Synthesis and Characterization of Cu (II), Ni (II), Mn (II), Zn (II) and Vo (II) Schiff base complexes derived from o-phenylenediamine and acetoacetanilide, Proc. Ind Acad. Sci., 113, 183-189. https://doi.org/10.1007/BF02704068.

      [29] Raman N., Dhaveethu Raja J. and Sakthivel A., 2007, Synthesis, spectral characterization of Schiff base transition metal complexes: DNA cleavage and antimicrobial activity studies, J. Chem. Sci., 119, 303-119. https://doi.org/10.1007/s12039-007-0041-5.

      [30] Rahman, M.S., Nasim Akter, H.M., Bakshi, P.K., Ehsan, M.Q., 2007. J. Saudi Chem. Soc. 11 (2), 277–286.

      [31] Rao, C.N.R., 1963. Chemical Applications of IR Spectroscopy. Academic Press, NY, p. 364.

      [32] Raman, N., Raja, S.J., Joseph, J. and Raja, J.D., 2006. Molecular Designing, Structura Elucidation, and Comparison of the Cleavage Ability of Oxovanadium (IV) Schiff Base Complexes, Russ. J. Coord. Chem., Vol. 33, No. 1, pp.7-11. https://doi.org/10.1134/S1070328407010022.

      [33] R.silverteins, F. Webster, 1998.Spectroscopic identification of organic compounds,sixth ed. John wiley and Sons, New York.

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    Musa, S., J F, I., & Musa Abubakar, S. (2019). Synthesis and characterization of iron (III) complexes of l-leucine and l-methionine. International Journal of Advanced Chemistry, 7(1), 73-76. https://doi.org/10.14419/ijac.v7i1.16098