The effect of long term physical exercises on plasma cortisol levels

  • Authors

    • Manoj Bandara Department of Pre Clinical Sciences, Faculty of Medicine,General Sir John Kotelawela Defence University Rathmalana Sri Lanka
    • Iresha Rathnayake Department of Pre Clinical Sciences, Faculty of Medicine,General Sir John Kotelawela Defence University Rathmalana Sri Lanka
    • Korotta Gamage Somasiri Department of Physiology, Faculty of Medicine, University of Ruhuna
    2017-09-26
    https://doi.org/10.14419/ijm.v5i2.8217
  • Long Term Exercises, Cortisol, Stress, Glucose, Health.
  • Regular physical exercises have shown to improve health. Stress can cause great impact on individual’s mental health as well as physical health. Plasma cortisol is used as a biomarker to measure stress. This study was carried out to evaluate the effect of long-term physical exercises on cortisol levels in healthy young men. The study was carried out on four study groups; non–exercised control group (NE), exercised for 6 months (E6M), exercised for 18 months (E18M) and exercised for 30 months (E30M). Thirty participants who underwent regular physical exercises for different time periods were included in each exercised group. Thirty controls were also recruited. Plasma cortisol was measured using ELIZA method and compared to the patterns of plasma glucose levels. Plasma cortisol levels of all exercised groups were significantly less than that of control group (p<0.05). A significant reduction of plasma cortisol level was observed in E6M (p<0.001) and E18 M (p<0.001). Plasma cortisol level of E30M was higher than E6M and E18M but less than the control group. Plasma glucose levels followed the same pattern as cortisol. The results of this study suggest that prolong exercises favorably alters the cortisol and glucose levels indicating reduced stress levels in young adults. The study clearly indicates that the prolong exercises have positive effect on the stress marker; plasma cortisol level as well as overall health of an individual.

  • References

    1. [1] Baum A (1990), Stress, Intrusive Imagery and Chronic Distress. Health Psychology 9, 653-675. https://doi.org/10.1037/0278-6133.9.6.653.

      [2] Berger BG, Friedmann E, & Eato M (1988), Comparison of Jogging, the Relaxation Response, and Group Interaction for Stress Reduction. Journal of sport and exercise physiology 10,431-447. https://doi.org/10.1123/jsep.10.4.431.

      [3] Lynch JJ (1975), the broken heart: The medical consequences of loneliness. New York: Basic Book.

      [4] Jenkins CD (1976), recent evidence supporting psychologic and social risk factors for coronary disease. New England Journal of Medicine 294, 987-994. https://doi.org/10.1056/NEJM197604292941806.

      [5] Maier SF & Laudenslager M (1985), Stress and health: Exploring the links. Psychology Today 19, 44-49.

      [6] Cornelissen VA & Fagard RH (2005). Effects of endurance training on blood pressure, blood pressure-regulating mechanisms and cardiovascular risk factors. Hypertension 46, 667-75. https://doi.org/10.1161/01.HYP.0000184225.05629.51.

      [7] Davis WJ, Wood DT, Andrews RG, Elkind LM & Davis WB (2008), Concurrent training enhances athletes' cardiovascular and cardiorespiratory measures. Journal of strength and conditioning research 22, 1503-1514. https://doi.org/10.1519/JSC.0b013e3181739f9f.

      [8] Choudhary SR & Binawara BK (2012) Effect of exercise on serum iron, blood haemoglobin and cardiac efficiency. Journal of Postgraduate Medical Institute 26,13-16

      [9] Bandara WMMS, Rathnayake AJIS, Basnayake BWMTJ, De Silva MKOK, Edirisinghe D & Somasiri KG (2016), Long term physical exercises improve cardiometabolic risk factors. Journal of Medical Science & Technology 5, 34 – 39.

      [10] Byrne A & Byrne DG (1993), The effect of exercise on depression, anxiety and other mood states: A review. Journal of Psychosomatic Research 37, 565–574. https://doi.org/10.1016/0022-3999(93)90050-P.

      [11] Salmon P (2001), Effects of physical exercise on anxiety, depression, and sensitivity to stress: A unifying theory. Clinical Psychology Review 21, 33-61. https://doi.org/10.1016/S0272-7358(99)00032-X.

      [12] Benton D & Thirlaway K (1992), Participation in physical activity and cardiovascular fitness have different effects on mental health and mood. Journal of Psychosomatic Research 36, 657–665. https://doi.org/10.1016/0022-3999(92)90055-7.

      [13] Hassmen P, Koivula N, Uutela A (2000), Physical Exercise and Psychological Well-Being: A Population Study in Finland. Preventive Medicine 30, 17–25. https://doi.org/10.1006/pmed.1999.0597.

      [14] Nguyen-Michel ST, Unger JB, Hamilton J & Spruijt-Metz D (2006), Associations between physical activity and perceived stress/hassles in college students. Stress and health 22, 179–188. https://doi.org/10.1002/smi.1094.

      [15] deVries HA (1968). Immediate and long-term effects of exercise upon resting muscle action potential level. Journal of Sports Medicine and Physical Fitness 8, 1–11.

      [16] Blumenthal JA, Sherwood A, Babyak MA, Watkins LL, Waugh R, Georgiades A, Bacon SL, Hayano J, Coleman RE & Hinderliter A (2005), Effects of exercise and stress management training on markers of cardiovascular risk in patients with ischemic heart disease. The Journal of the American Medical Association 293, 1626-1634. https://doi.org/10.1001/jama.293.13.1626.

      [17] Lalanza JF, Sanchez-Roige S, Cigarroa I, Gagliano H, Fuentes S, Armario A, Capdevila L & Escorihuela RM (2015), Long-term moderate treadmill exercise promotes stress-coping strategies in male and female rats. Scientific reports, 5-16166. https://doi.org/10.1038/srep16166.

      [18] Lee DY, Kim E & Choi MH (2015), Technical and clinical aspects of cortisol as a biochemical marker of chronic stress. BMB Reports 48, 209-216. https://doi.org/10.5483/BMBRep.2015.48.4.275.

      [19] Kuoppasalmi K, Näveri H, Härkönen M & Adlercreutz H (1980), Plasma cortisol, androstenedione, testosterone and luteinizing hormone in running exercise of different intensities, Scandinavian Journal of Clinical Laboratory Investigation 40, 403–409. https://doi.org/10.3109/00365518009101862.

      [20] Brown BS & Van Huss W (1973). Exercise and rat brain catecholamines. Journal of Applied Physiology, 34,664–669.

      [21] Brown BS, Payne T, Kim C, Moore G, Krebs P & Martin W (1979), chronic response of rat brain norepinephrine and serotonin levels to endurance training. Journal of applied physiology 46, 19-23.

      [22] Dishman RK, Renner KJ, Youngstedt SD, Reigle TG, Bunnell BN, Burke KA, Yoo HS, Mougey EH & Meyerhof JL (1997), Activity wheel running reduces escape latency and alters brain monoamine levels after footshock. Brain Research Bulletin 42, 399–406. https://doi.org/10.1016/S0361-9230(96)00329-2.

      [23] Khani S & John A (2001). Cortisol increases gluconeogenesis in humans: its role in the metabolic syndrome. Clinical Science 101,739–747. https://doi.org/10.1042/cs1010739.

      [24] Dmitrašinović G, Pešić V, Stanić D, Plećaš-Solarović B, Dajak M & Ignjatović S (2016), ACTH, Cortisol and IL-6 Levels in Athletes following Magnesium Supplementation. Journal of Medical Biochemistry 35, 375-384. https://doi.org/10.1515/jomb-2016-0021.

      [25] Keselman B, Vergara M, Nyberg S & Nystrom FH (2017), A randomized cross-over study of the acute effects of running 5 km on glucose, insulin, metabolic rate, cortisol and Troponin T. PLoS One, 16;12(6):e0179401. doi:10.1371/journal.pone. 0179401.

      [26] Slimani M, Cheour F, Moalla W & Baker JS (2017). Hormonal responses to a rugby match: a brief review. The Journal of Sports Medicine and Physical Fitness, doi: 10.23736/S0022-4707.17.07187-0.

      [27] Verbickas V, Baranauskiene N, Eimantas N, Kamandulis S, Rutkauskas S, Satkunskiene D, Sadauskas S, Brazaitis M & Skurvydas A (2017), Effect of sprint cycling and stretch-shortening cycle exercises on the neuromuscular, immune and stress indicators in young men. Journal of Physiology and Pharmacology 68,125-132.

      [28] Haugland S, Wold B & Torsheim T (2003), relieving the pressure? The role of physical activity in the relationship between school-related stress and adolescent health complaints. Research Quarterly for Exercise and Sport 74, 127-135. https://doi.org/10.1080/02701367.2003.10609074.

      [29] Thome J & Espelage DL (2004), Relations among exercise, coping, disordered eating, and psychological health among college students. Eating Behaviors 5, 337-351. https://doi.org/10.1016/j.eatbeh.2004.04.002.

      [30] Hill RD, Storandt M & Malley M (1993), The Impact of Long-term Exercise Training on Psychological Function in Older Adults. Journal of Gerontology 48, 12-P7. https://doi.org/10.1093/geronj/48.1.P12.

      [31] Hackney AC (2006), Stress and the neuroendocrine system: the role of exercise as a stressor and modifier of stress. Expert Review of Endocrinology & Metabolism 1, 783-92. https://doi.org/10.1586/17446651.1.6.783.

      [32] Wittert G, Livesey JH, Espiner EA & Donald RA (1996). Adaptation of the hypothalamopituitary adrenal axis to chronic exercise stress in humans. Medicine and Science in Sports and Exercise 28, 1015-1019. https://doi.org/10.1097/00005768-199608000-00011.

      [33] McMurray RG & Hackney AC (2000), Endocrine responses to exercise and training. Exercise and sport science, Philadelphia, Lippincott Williams & Wilkins. 135-61.

      [34] Lal K (2014), Academic stress among adolescent in relation to intelligence and demographic factors. American International Journal of Research in Humanities, Arts and Social Sciences, 123-129.

      [35] Deb S, Strodl E & Sun J (2015), Academic Stress, Parental Pressure, Anxiety and Mental Health among Indian High School Students. International Journal of Psychology and Behavioral Sciences 5, 26-34.

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    Bandara, M., Rathnayake, I., & Somasiri, K. G. (2017). The effect of long term physical exercises on plasma cortisol levels. International Journal of Medicine, 5(2), 239-242. https://doi.org/10.14419/ijm.v5i2.8217