Impact of Radiotherapy Treatment on Jordanian Cancer Patients Quality of Life and Fatigue

 
 
 
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  • Abstract


    Background: The distressing treatment of cancer whether chemotherapy or radiotherapy is associated with fatigue and has negative impact on patient quality of life (QOL).

    Objectives: The purposes of this study were to examine the impact of radiotherapy treatment on Jordanian cancer patients QOL and fatigue, and to explore the relationship between fatigue and QOL.

    Methods: One group quasi-experimental correlational design was used with 82 patients who had been diagnosed with cancer and required radiotherapy treatment. QOL was measured using the Functional Assessment of Cancer Therapy-General (FACT-G). Fatigue was measured using Piper Fatigue Scale (PFS). Data were collected over a period of three months, and analyzed using Pearson Product Moment Correlation, descriptive statistics and paired-sample t-test.

    Results: Significant differences were found between pre- and post- radiotherapy QOL mean total scores (t=19.3, df=79, P<0.05), as well as physical, emotional, sexual, and functional wellbeing dimensions. Statistically significant differences were found between pre- and post- radiotherapy fatigue mean total scores (t=-8.95, df=79, P<0.05), as well as on behavioral, affective, sensory, and cognitive dimensions of PFS. Quality of life total scores correlated significantly and negatively with total fatigue scores (P<0.01).

    Conclusions: Exposure of cancer patient to radiotherapy treatment increased their fatigue level and decreased their QOL. Nurses should assess cancer patients before, during, and after their treatment to design proper interventions to reduce fatigue and enhance QOL.


  • References


    1. Ahlberg K , Ekman T & Gaston-Johansson F (2005), The experience of fatigue, other symptoms and global quality of life during radiotherapy for uterine cancer. International Journal of Nursing Studies 42, 377-386.
    2. Ahlberg K , Ekman T , Gaston-Johansson F & Mock V (2003), Assessment and management of cancer-related fatigue in adults. The Lancet 362, 640-650.
    3. Ahmad MM, Alasad JA & Nawa?eh H (2010), Nursing care and quality of life among Jordanian patients with cancer. Leadership in Health Services 23, 233-243.
    4. Ahmed Q, Memish Z, Allegranzi B, Pittet D & Challenge W (2006), Muslim health care workers and alcohol based handrubs. Lancet 367, 1025-1027.
    5. Aistar J (1987), Fatigue in Cancer patients: a conceptual approach to clinical problem. Oncology Nursing Forum 14, 25-30.
    6. Alhalaiqa F, Deane K, Nawafleh A, Clark A & Gray R (2012), Adherence therapy for medication non-compliant patients with hypertension: a randomised controlled trial. Journal of Human Hypertension 26, 117-126.
    7. Armstrong C, Mollman J, Corn B, Alavi J & Grossman L (1993), Effects of radiation therapy on adult behavior: Evidence for a rebound phenomenon in a phase 1 trial. Neurology 43, 1961-1965.
    8. Barakat H (1993). The Arab World: Society, Culture and State. Burkely: university of California press.
    9. Batiha A-M & AL Bashtawy M (2013), Knowledge of Philadelphia University students regarding blood Donation. Transfusion Medicine 23, 195198.
    10. Batiha A-M (2012), Pain Management Barriers in Jordanian Critical Care Units. International Journal of Advanced Nursing Studies 1(2), 73-83.
    11. Batiha A-M, Bashaireh I, Albashtawy M & Shennaq S (2013), explores the competency of the Jordanian intensive care nurses towards endotracheal tube and oral care practices for mechanically ventilated patients: an observational study. Global Journal of Health Science 5, 203-213.
    12. Bjordal K & Kaasa S (1995), Psychological distress in head and neck cancer patients 7-11 years after curative treatment. Br J Cancer 71, 592-597.
    13. Bower JE, Ganz PA, Desmond KA, Rowland JH, Meyerowitz BE & Belin TR (2000), Fatigue in Breast Cancer Survivors: Occurrence, Correlates, and Impact on Quality of Life. Journal of Clinical Oncology 18, 743.
    14. Brown P , Clark M , Atherton P , Huschka M , Sloan J , Gamble G , Girardi J , Frost M , Piderman K & Rummans T (2006), Will improvement in quality of life (QOL) impact fatigue in patients receiving radiation therapy for advanced cancer. American Journal of Clinical Oncology 29, 52-58.
    15. Bruheim K , Guren MG , Skovlund E , Hjermstad MJ , Dahl O , Frykholm G , Carlsen E & Tveit KM (2010), Late Side Effects and Quality of Life After Radiotherapy for Rectal Cancer. International Journal of Radiation Oncology*Biology*Physics 76, 1005-1011.
    16. Cella D (1997), The Functional Assessment of Cancer Therapy-Anemia (FACT-An) Scale: a new tool for the assessment of outcomes in cancer anemia and fatigue. Seminars in hematology 34, 13-19.
    17. Cella DF & Tulsky DS (1990), Measuring quality of life today: methodological aspects. Oncology (Williston Park, N.Y.) 4, 29-38; discussion 69.
    18. Cohen J (1988), Statistical power analysis for the behavioral science Hillsdale, N.J: Lwarence Eribaum.
    19. Curt GA, Breitbart W, Cella D, Groopman JE, Horning SJ, Itri LM, Johnson DH, Miaskowski C, Scherr SL, Portenoy RK & Vogelzang NJ (2000), Impact of cancer related fatigue on the lives of patients: new findings from the fatigue coaliation. The Oncologist 5, 353-360.
    20. de Graeff A , de Leeuw JRJ , Ros WJG , Hordijk G-J , Blijham GH & Winnubst JAM (2000), Long-Term Quality of Life of Patients With Head and Neck Cancer. The Laryngoscope 110, 98-106.
    21. Ferrel B, Dow K, Leigh L & Gulasekarm P (1995), Quality of life in long term cancer survivors. Oncology Nursing Forum 22, 915-922.
    22. Glaus A, Crow R & Hammond S (1996), a qualitative study to explore the concept of fatigue/tiredness in cancer patients and in healthy individuals. Supportive Care in Cancer 4, 82-96.
    23. Grant M, Dean G, Funk B & Ferrell B (1996), Bone tired: the experience of fatigue and impact on QOL. Oncology Nursing Forum 23, 539-1547.
    24. Grant M, Ferrell B, Dean G, Uman G, Chu D & Krouse R (2004), Revision and psychometric testing of the City of Hope Quality of Life-Ostomy Questionnaire. Quality of Life Research 13, 1445-1457.
    25. Gupta D , Lis CG & Grutsch JF (2007), The Relationship Between Cancer-Related Fatigue and Patient Satisfaction with Quality of Life in Cancer. Journal of Pain and Symptom Management 34, 40-47.
    26. Guren MG , Dueland S , Skovlund E , Foss SD , Poulsen JP & Tveit KM (2003), Quality of life during radiotherapy for rectal cancer. European Journal of Cancer 39, 587-594.
    27. Haberman M (1995), the meaning of cancer therapy: Bone marrow transplantation as an exemplar of therapy. Seminars in Oncology Nursing 11, 23-31.
    28. Janaki M , Kadam A , Mukesh S , Nirmala S , Ponni A , Ramesh B & Rajeev A (2010), Magnitude of fatigue in cancer patients receiving radiotherapy and its short term effect on quality of life. Journal of Cancer Research and Therapeutics 6, 22-26.
    29. Jemal A, Bray F, Center MM, Ferlay J, Ward E & Forman D (2011), Global cancer statistics. A Cancer Journal for Clinicians 61, 69-90.
    30. Jensen PT, Groenvold M, Klee MC, Thranov I, Petersen MA & Machin D (2003), Longitudinal study of sexual function and vaginal changes after radiotherapy for cervical cancer. International Journal of Radiation Oncology*Biology*Physics 56, 937-949.
    31. Jordanian Cancer Regisrty (2008), National cancer statistics, Cancer Incidence in Jordan. http://www.khcc.jo/National_cancer_statistics.aspx.
    32. Klein M , Heimans JJ , Aaronson NK , van der Ploeg HM , Grit J , Muller M , Postma TJ , Mooij JJ , Boerman RH , Beute GN , Ossenkoppele GJ , van Imhoff GW , Dekker AW , Jolles J , Slotman BJ , Struikmans H & Taphoorn MJB (2002), Effect of radiotherapy and other treatment-related factors on mid-term to long-term cognitive sequelae in low-grade gliomas: a comparative study. The Lancet 360, 1361-1368.
    33. Labourey JL (2007), Physical activity in the management of cancer-related fatigue induced by oncological treatments. Annales de Radaptation et de Mdecine Physique 50, 450-454.
    34. Mackillop WJ, Stewart WE, Ginsburg AD & Stewart SS (1988), Cancer patients' perceptions of their disease and its treatment. British journal of cancer 58, 355-358.
    35. Maneesriwongul W & Dixon J (2004), Instrument translation process: a methods review. Journal of Advanced Nursing 48, 175-186.
    36. National Cancer Institue (2012), Factors Affecting Sexual Function in People With Cancer. http://www.cancer.gov/cancertopics/pdq/supportivecare/sexuality/HealthProfessional/page2.
    37. National Comprehensive Cancer Network (2010), NCCN Clinical Practice Guidelines in Oncology: Cancer-related fatigue. http://www.nccn.org/professionals/physician_gls/ PDF/fatigue.pdf.
    38. Ozlines U (2009), Back translation as a means of giving translators a voice. The International Journal for Translation and Interpreting 1(2), 1-15.
    39. Piper B , Dibble S , Dodd M , Weiss M , Slaughter R & Paul S (1998), The revised piper fatigue scale: psychometric evaluation in women with breast cancer. Oncology Nursing Forum 25, 677-684.
    40. Prue G , Rankin J , Allen J , Gracey J & Cramp F (2006), Cancer-related fatigue: A critical appraisal. European Journal of Cancer 42, 846-863.
    41. Smets E, Garssen B, Cull A & de Haes J (1996), Application of the multidimensional fatigue inventory (MFI-20) in cancer patients receiving radiotherapy. British journal of cancer 73, 241-245.
    42. So WKW, Dodgson J & Tai JWM (2003), Fatigue and quality of life among Chinese patients with hematologic malignancy after bone marrow transplantation. Cancer Nursing 26, 211-219.
    43. SDerberg SIV, Lundman B & Norberg A (2002), The meaning of fatigue and tiredness as narrated by women with fibromyalgia and healthy women. Journal of Clinical Nursing 11, 247-255.
    44. Taphoorn M (1994), Cognitive functions and QOL in-patients with low-grade gliomas: The impact of radiotherapy. Neurology 36, 48-54.
    45. Tawalbeh L, Ahmad Tubaishat A, Batiha A-M, Manar Al-Azzam M & AlBashtawy M (2013), The Relationship Between Social Support and Adherence to Healthy Lifestyle Among Patients With Coronary Artery Disease in the North of Jordan Clinical Nursing Research. DOI: 10.1177/1054773813501194.
    46. Visser M & Smets E (1998), Fatigue, depression and quality of life in cancer patients: how are they related? Support Care Cancer 6, 101-108.
    47. Vogelzang NJ, Breitbart W, Cella D, Curt GA, Groopman JE, Horning SJ, Itri LM, Johnson DH, Scherr SL & Portenoy RK (1997), Patient, caregiver, and oncologist perceptions of cancer-related fatigue: results of a tripart assessment survey. The Fatigue Coalition. Seminars in hematology 34, 4-12.
    48. Whedon M , Stearns D & Mills LE (1995), Quality of life of long-term adult survivors of autologous bone marrow transplantation. Oncology Nursing Forum 22, 1527-1535; discussion 1535-1527.
    49. WHO (2008). World cancer report. http://www.iarc.fr/en/publications/pdfs-online/wcr/2008/index.php.
    50. WHO (2009). 2008-2013 Action plan for the global strategy for the prevention and control of noncommunicable diseases, World Health Organisation. http://whqlibdoc.who.int/publications/2009/9789241597418_eng.pdf. (Accessed 2/11/2013).
    51. Yoel U, Abu- Behind the scenes of adherence in a minority population. Israel Hammed T , Cohen A , Aizenberg A , Vardy D & Shvartzman P (2013), Medical Association Journal: Imaj 15, 17-22.

 

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Article ID: 798
 
DOI: 10.14419/ijans.v3i1.798




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